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Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells

Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3419307

Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells

About this item

Full title

Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells

Publisher

London: BMJ Publishing Group Ltd and British Society of Gastroenterology

Journal title

Gut, 2012-09, Vol.61 (9), p.1250-1260

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group Ltd and British Society of Gastroenterology

More information

Scope and Contents

Contents

ObjectiveExposure of the oesophageal mucosa to gastric acid and bile acids leads to the accumulation of reactive oxygen species (ROS), a known risk factor for Barrett's oesophagus and progression to oesophageal adenocarcinoma (OAC). This study investigated the functions of glutathione peroxidase 7 (GPX7), frequently silenced in OAC, and its capacit...

Alternative Titles

Full title

Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3419307

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3419307

Other Identifiers

ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2011-301078

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