Glypican-4 Enhances Insulin Signaling via Interaction With the Insulin Receptor and Serves as a Nove...
Glypican-4 Enhances Insulin Signaling via Interaction With the Insulin Receptor and Serves as a Novel Adipokine
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Publisher
Alexandria, VA: American Diabetes Association
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Language
English
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Publisher
Alexandria, VA: American Diabetes Association
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Scope and Contents
Contents
Obesity, especially visceral obesity, is associated with insulin resistance and metabolic syndrome. We previously identified the cell surface proteoglycan glypican-4 as differentially expressed in subcutaneous versus visceral white fat depots. Here we show that glypican-4 is released from cells and adipose tissue explants of mice, and that circulat...
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Full title
Glypican-4 Enhances Insulin Signaling via Interaction With the Insulin Receptor and Serves as a Novel Adipokine
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3425403
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3425403
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db11-1395