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A restricted cell population propagates glioblastoma growth following chemotherapy

A restricted cell population propagates glioblastoma growth following chemotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3427400

A restricted cell population propagates glioblastoma growth following chemotherapy

About this item

Full title

A restricted cell population propagates glioblastoma growth following chemotherapy

Journal title

Nature (London), 2012-08, Vol.488 (7412), p.522-526

Language

English

Formats

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Scope and Contents

Contents

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, with a median survival of about one year
1
. This poor prognosis is due to therapeutic resistance and tumor recurrence following surgical removal. Precisely how recurrence occurs is unknown. Using a genetically-engineered mouse model of glioma, we identify a subse...

Alternative Titles

Full title

A restricted cell population propagates glioblastoma growth following chemotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3427400

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3427400

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature11287

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