Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo
Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo
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Full title
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Publisher
United States: Elsevier Inc
Journal title
Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Mitochondrial abnormalities have been documented in Alzheimer’s disease and related neurodegenerative disorders, but the causal relationship between mitochondrial changes and neurodegeneration, and the specific mechanisms promoting mitochondrial dysfunction, are unclear. Here, we find that expression of human tau results in elongation of mitochondr...
Alternative Titles
Full title
Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo
Authors, Artists and Contributors
Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3428596
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3428596
Other Identifiers
ISSN
0896-6273
E-ISSN
1097-4199
DOI
10.1016/j.neuron.2012.06.026
