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Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3433955

Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

About this item

Full title

Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2012-04, Vol.8 (6), p.562-568

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Bacteria must control their metabolism to quickly adapt to changing carbon sources. PEP carboxylase is now shown to be allosterically regulated by fructose-1,6-bisphosphate in an ultrasensitive manner, turning glycolysis on and off almost instantaneously in response to glucose availability.
Anapleurosis is the filling of the tricarboxylic acid c...

Alternative Titles

Full title

Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3433955

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3433955

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.941

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