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Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II–induced card...

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II–induced card...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3434275

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II–induced cardiac, renal, and vascular injury

About this item

Full title

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II–induced cardiac, renal, and vascular injury

Publisher

Basingstoke: Elsevier Inc

Journal title

Kidney international, 2012-09, Vol.82 (6), p.643-651

Language

English

Formats

Publication information

Publisher

Basingstoke: Elsevier Inc

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Angiotensin II causes cardiovascular injury in part by aldosterone-induced mineralocorticoid receptor activation, and it can also activate the mineralocorticoid receptor in the absence of aldosterone in vitro. Here we tested whether endogenous aldosterone contributes to angiotensin II/salt-induced cardiac, vascular, and renal injury by the mineralo...

Alternative Titles

Full title

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II–induced cardiac, renal, and vascular injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3434275

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3434275

Other Identifiers

ISSN

0085-2538

E-ISSN

1523-1755

DOI

10.1038/ki.2012.170

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