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A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to h...

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to h...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3442275

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors

About this item

Full title

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2012-09, Vol.31 (18), p.3704-3717

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Understanding the cellular origin of cancer can help to improve disease prevention and therapeutics. Human plasma cell neoplasias are thought to develop from either differentiated B cells or plasma cells. However, when the expression of
Maf
oncogenes (associated to human plasma cell neoplasias) is targeted to mouse B cells, the resulting anim...

Alternative Titles

Full title

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3442275

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3442275

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2012.227

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