Myostatin Inhibition Prevents Diabetes and Hyperphagia in a Mouse Model of Lipodystrophy
Myostatin Inhibition Prevents Diabetes and Hyperphagia in a Mouse Model of Lipodystrophy
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Publisher
Alexandria, VA: American Diabetes Association
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Language
English
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Publisher
Alexandria, VA: American Diabetes Association
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Scope and Contents
Contents
Lipodystrophies are characterized by a loss of white adipose tissue, which causes ectopic lipid deposition, peripheral insulin resistance, reduced adipokine levels, and increased food intake (hyperphagia). The growth factor myostatin (MSTN) negatively regulates skeletal muscle growth, and mice with MSTN inhibition have reduced adiposity and improve...
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Full title
Myostatin Inhibition Prevents Diabetes and Hyperphagia in a Mouse Model of Lipodystrophy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3447905
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3447905
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db11-0915
