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Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3461906

Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

About this item

Full title

Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2012-10, Vol.122 (10), p.3705-3717

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The transcription factor GATA-2 plays vital roles in quite diverse developmental programs, including hematopoietic stem cell (HSC) survival and proliferation. We previously identified a vascular endothelial (VE) enhancer that regulates GATA-2 activity in pan-endothelial cells. To more thoroughly define the in vivo regulatory properties of this enha...

Alternative Titles

Full title

Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3461906

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3461906

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI61619

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