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Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3461920

Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

About this item

Full title

Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2012-10, Vol.122 (10), p.3737-3741

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The osteoporosis associated with human hyperthyroidism has traditionally been attributed to elevated thyroid hormone levels. There is evidence, however, that thyroid-stimulating hormone (TSH), which is low in most hyperthyroid states, directly affects the skeleton. Importantly, Tshr-knockout mice are osteopenic. In order to determine whether low TS...

Alternative Titles

Full title

Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3461920

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3461920

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI63948

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