Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase
Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase
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Author / Creator
Publisher
Cairo, Egypt: Hindawi Puplishing Corporation
Journal title
Language
English
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Publication information
Publisher
Cairo, Egypt: Hindawi Puplishing Corporation
Subjects
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Scope and Contents
Contents
Impaired activity of the lysosomal enzyme glucocerebrosidase (GCR) results in the inherited metabolic disorder known as Gaucher disease. Current treatment consists of enzyme replacement therapy by administration of exogenous GCR. Although effective, it is exceptionally expensive, and patients worldwide have a limited access to this medicine. In Bra...
Alternative Titles
Full title
Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3471063
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3471063
Other Identifiers
ISSN
1110-7243,2314-6133
E-ISSN
1110-7251,2314-6141
DOI
10.1155/2012/875383
