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AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3474921

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Following genotoxic stress, cells activate a complex signalling network to arrest the cell cycle and initiate DNA repair or apoptosis. The tumour suppressor p53 lies at the heart of this DNA damage response. However, it remains incompletely understood, which signalling molecules dictate the choice between these different cellular outcomes. Here, we...

Alternative Titles

Full title

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3474921

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3474921

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2012.236

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