AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis
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Author / Creator
Höpker, Katja , Hagmann, Henning , Khurshid, Safiya , Chen, Shuhua , Hasskamp, Pia , Seeger-Nukpezah, Tamina , Schilberg, Katharina , Heukamp, Lukas , Lamkemeyer, Tobias , Sos, Martin L , Thomas, Roman K , Lowery, Drew , Roels, Frederik , Fischer, Matthias , Liebau, Max C , Resch, Ulrike , Kisner, Tülay , Röther, Fabian , Bartram, Malte P , Müller, Roman Ulrich , Fabretti, Francesca , Kurschat, Peter , Schumacher, Björn , Gaestel, Matthias , Medema, René H , Yaffe, Michael B , Schermer, Bernhard , Reinhardt, H Christian and Benzing, Thomas
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
Following genotoxic stress, cells activate a complex signalling network to arrest the cell cycle and initiate DNA repair or apoptosis. The tumour suppressor p53 lies at the heart of this DNA damage response. However, it remains incompletely understood, which signalling molecules dictate the choice between these different cellular outcomes. Here, we...
Alternative Titles
Full title
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis
Authors, Artists and Contributors
Author / Creator
Hagmann, Henning
Khurshid, Safiya
Chen, Shuhua
Hasskamp, Pia
Seeger-Nukpezah, Tamina
Schilberg, Katharina
Heukamp, Lukas
Lamkemeyer, Tobias
Sos, Martin L
Thomas, Roman K
Lowery, Drew
Roels, Frederik
Fischer, Matthias
Liebau, Max C
Resch, Ulrike
Kisner, Tülay
Röther, Fabian
Bartram, Malte P
Müller, Roman Ulrich
Fabretti, Francesca
Kurschat, Peter
Schumacher, Björn
Gaestel, Matthias
Medema, René H
Yaffe, Michael B
Schermer, Bernhard
Reinhardt, H Christian
Benzing, Thomas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3474921
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3474921
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2012.236