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Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells f...

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells f...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3479579

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3⁺ regulatory T cells

About this item

Full title

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3⁺ regulatory T cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (40), p.16258-16263

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Several lines of evidence suggest nuclear factor of activated T-cells (NFAT) to control regulatory T cells: thymus-derived naturally occurring regulatory T cells (nTreg) depend on calcium signals, the Foxp3 gene harbors several NFAT binding sites, and the Foxp3 (Fork head box P3) protein interacts with NFAT. Therefore, we investigated the impact of...

Alternative Titles

Full title

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3⁺ regulatory T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3479579

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3479579

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1203870109

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