Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells f...
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3⁺ regulatory T cells
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Several lines of evidence suggest nuclear factor of activated T-cells (NFAT) to control regulatory T cells: thymus-derived naturally occurring regulatory T cells (nTreg) depend on calcium signals, the Foxp3 gene harbors several NFAT binding sites, and the Foxp3 (Fork head box P3) protein interacts with NFAT. Therefore, we investigated the impact of...
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Full title
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3⁺ regulatory T cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3479579
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3479579
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1203870109