Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic ce...
Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The homeodomain transcription factor Nanog plays an important role in embryonic stem cell (ESC) self-renewal and is essential for acquiring ground-state pluripotency during reprogramming. Understanding how Nanog is transcriptionally regulated is important for further dissecting mechanisms of ESC pluripotency and somatic cell reprogramming. Here, we...
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Full title
Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3479613
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3479613
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1208533109