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Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3484444

Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

About this item

Full title

Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2012-11, Vol.122 (11), p.3931-3942

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

DC-mediated NKT cell activation is critical in initiating the immune response following kidney ischemia/reperfusion injury (IRI), which mimics human acute kidney injury (AKI). Adenosine is an important antiinflammatory molecule in tissue inflammation, and adenosine 2A receptor (A₂AR) agonists protect kidneys from IRI through their actions on leukoc...

Alternative Titles

Full title

Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3484444

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3484444

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI63170

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