First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherap...
First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial
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Author / Creator
Lee, Siow Ming, Prof , Khan, Iftekhar, MSc , Upadhyay, Sunil, MD , Lewanski, Conrad, FRCP , Falk, Stephen, MD , Skailes, Geraldine, FRCR , Marshall, Ernie, MD , Woll, Penella J, Prof , Hatton, Matthew, FRCR , Lal, Rohit, MRCP , Jones, Richard, FRCR , Toy, Elizabeth, FRCR , Chao, David, DPhil , Middleton, Gary, MD , Bulley, Sue, SRN , Ngai, Yenting, BSc , Rudd, Robin, MD , Hackshaw, Allan, Prof and Boshoff, Chris, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Many patients with advanced non-small-cell lung cancer (NSCLC) receive only active supportive care because of poor performance status or presence of several comorbidities. We investigated whether erlotinib improves clinical outcome in these patients. Methods TOPICAL was a double-blind, randomised, placebo-controlled, phase 3 tria...
Alternative Titles
Full title
First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Khan, Iftekhar, MSc
Upadhyay, Sunil, MD
Lewanski, Conrad, FRCP
Falk, Stephen, MD
Skailes, Geraldine, FRCR
Marshall, Ernie, MD
Woll, Penella J, Prof
Hatton, Matthew, FRCR
Lal, Rohit, MRCP
Jones, Richard, FRCR
Toy, Elizabeth, FRCR
Chao, David, DPhil
Middleton, Gary, MD
Bulley, Sue, SRN
Ngai, Yenting, BSc
Rudd, Robin, MD
Hackshaw, Allan, Prof
Boshoff, Chris, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3488187
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3488187
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(12)70412-6
