Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist
Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The authors determine the crystal structure of the extracellular domain of a receptor chimera constructed from the human α
7
acetylcholine receptor (AChR) and acetylcholine binding protein (AChBP), as well as the structure with bound epibatidine, a potent AChR agonist. The structures provide a realistic template for structure-aided drug desig...
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Full title
Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3489043
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3489043
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2908
