Multigenerational epigenetic adaptation of the hepatic wound-healing response
Multigenerational epigenetic adaptation of the hepatic wound-healing response
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Derek Mann and his colleagues have found that experimental induction of liver fibrosis in male rats results in an epigenetic modification of the chromatin in their sperm such that their offspring have a more mild wound-healing response to hepatic fibrogenic insults. The mechanism responsible for this phenomenon is not clear, but it seems to involve...
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Full title
Multigenerational epigenetic adaptation of the hepatic wound-healing response
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3489975
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3489975
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2893
