Evolution of the human-specific microRNA miR-941
Evolution of the human-specific microRNA miR-941
About this item
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Author / Creator
Hu, Hai Yang , He, Liu , Fominykh, Kseniya , Yan, Zheng , Guo, Song , Zhang, Xiaoyu , Taylor, Martin S. , Tang, Lin , Li, Jie , Liu, Jianmei , Wang, Wen , Yu, Haijing and Khaitovich, Philipp
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
MicroRNA-mediated gene regulation is important in many physiological processes. Here we explore the roles of a microRNA, miR-941, in human evolution. We find that miR-941 emerged
de novo
in the human lineage, between six and one million years ago, from an evolutionarily volatile tandem repeat sequence. Its copy-number remains polymorphic in h...
Alternative Titles
Full title
Evolution of the human-specific microRNA miR-941
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3493648
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3493648
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms2146
