Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithe...
Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
About this item
Full title
Author / Creator
Abkevich, V , Timms, K M , Hennessy, B T , Potter, J , Carey, M S , Meyer, L A , Smith-McCune, K , Broaddus, R , Lu, K H , Chen, J , Tran, T V , Williams, D , Iliev, D , Jammulapati, S , FitzGerald, L M , Krivak, T , DeLoia, J A , Gutin, A , Mills, G B and Lanchbury, J S
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background:
Defects in
BRCA1
,
BRCA2
, and other members of the homologous recombination pathway have potential therapeutic relevance when used to support agents that introduce or exploit double-stranded DNA breaks. This study examines the association between homologous recombination defects and genomic patterns of loss of heterozygo...
Alternative Titles
Full title
Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3493866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3493866
Other Identifiers
ISSN
0007-0920,1532-1827
E-ISSN
1532-1827
DOI
10.1038/bjc.2012.451
