BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice
BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice
About this item
Full title
Author / Creator
Fukui, H. , Wong, H. T. , Beyer, L. A. , Case, B. G. , Swiderski, D. L. , Di Polo, A. , Ryan, A. F. and Raphael, Y.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Current therapy for patients with hereditary absence of cochlear hair cells, who have severe or profound deafness, is restricted to cochlear implantation, a procedure that requires survival of the auditory nerve. Mouse mutations that serve as models for genetic deafness can be utilized for developing and enhancing therapies for hereditary deafness....
Alternative Titles
Full title
BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3495341
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3495341
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep00838
