Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome for...
Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Scope and Contents
Contents
Autophagy is a conserved process for the bulk degradation of cytoplasmic material. Triggering of autophagy results in the formation of double membrane‐bound vesicles termed autophagosomes. The conserved Atg5–Atg12/Atg16 complex is essential for autophagosome formation. Here, we show that the yeast Atg5–Atg12/Atg16 complex directly binds membranes....
Alternative Titles
Full title
Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3501226
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3501226
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2012.278
