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Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pe...

Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3509994

Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pellets supported on SBA-15 mesoporous silica

About this item

Full title

Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pellets supported on SBA-15 mesoporous silica

Publisher

New Zealand: Taylor & Francis Ltd

Journal title

International journal of nanomedicine, 2012-01, Vol.7, p.5807-5818

Language

English

Formats

Publication information

Publisher

New Zealand: Taylor & Francis Ltd

More information

Scope and Contents

Contents

The aim of this study was to develop an immediate-release pellet formulation with improved drug dissolution and adsorption. Carbamazepine, a poorly water-soluble drug, was adsorbed into mesoporous silica (SBA-15-CBZ) via a wetness impregnation method and then processed by extrusion/spheronization into pellets. Physicochemical characterization of th...

Alternative Titles

Full title

Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pellets supported on SBA-15 mesoporous silica

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3509994

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3509994

Other Identifiers

ISSN

1178-2013,1176-9114

E-ISSN

1178-2013

DOI

10.2147/IJN.S37650

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