Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadi...
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
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Author / Creator
Alzheimer's Disease Genetics Consortium , Whitcomb, David C , LaRusch, Jessica , Krasinskas, Alyssa M , Klei, Lambertus , Smith, Jill P , Brand, Randall E , Neoptolemos, John P , Lerch, Markus M , Tector, Matt , Sandhu, Bimaljit S , Guda, Nalini M , Orlichenko, Lidiya , Alkaade, Samer , Amann, Stephen T , Anderson, Michelle A , Baillie, John , Banks, Peter A , Conwell, Darwin , Coté, Gregory A , Cotton, Peter B , DiSario, James , Farrer, Lindsay A , Forsmark, Chris E , Johnstone, Marianne , Gardner, Timothy B , Gelrud, Andres , Greenhalf, William , Haines, Jonathan L , Hartman, Douglas J , Hawes, Robert A , Lawrence, Christopher , Lewis, Michele , Mayerle, Julia , Mayeux, Richard , Melhem, Nadine M , Money, Mary E , Muniraj, Thiruvengadam , Papachristou, Georgios I , Pericak-Vance, Margaret A , Romagnuolo, Joseph , Schellenberg, Gerard D , Sherman, Stuart , Simon, Peter , Singh, Vijay P , Slivka, Adam , Stolz, Donna , Sutton, Robert , Weiss, Frank Ulrich , Wilcox, C Mel , Zarnescu, Narcis Octavian , Wisniewski, Stephen R , O'Connell, Michael R , Kienholz, Michelle L , Roeder, Kathryn , Barmada, M Michael , Yadav, Dhiraj and Devlin, Bernie
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
David Whitcomb, Bernie Devlin and colleagues report the results of a genome-wide association study of pancreatitis. They identify common variants at two loci associated with risk of this disease, including one on the X chromosome that shows strong evidence of interaction with alcohol consumption.
Pancreatitis is a complex, progressively destruct...
Alternative Titles
Full title
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
Authors, Artists and Contributors
Author / Creator
Whitcomb, David C
LaRusch, Jessica
Krasinskas, Alyssa M
Klei, Lambertus
Smith, Jill P
Brand, Randall E
Neoptolemos, John P
Lerch, Markus M
Tector, Matt
Sandhu, Bimaljit S
Guda, Nalini M
Orlichenko, Lidiya
Alkaade, Samer
Amann, Stephen T
Anderson, Michelle A
Baillie, John
Banks, Peter A
Conwell, Darwin
Coté, Gregory A
Cotton, Peter B
DiSario, James
Farrer, Lindsay A
Forsmark, Chris E
Johnstone, Marianne
Gardner, Timothy B
Gelrud, Andres
Greenhalf, William
Haines, Jonathan L
Hartman, Douglas J
Hawes, Robert A
Lawrence, Christopher
Lewis, Michele
Mayerle, Julia
Mayeux, Richard
Melhem, Nadine M
Money, Mary E
Muniraj, Thiruvengadam
Papachristou, Georgios I
Pericak-Vance, Margaret A
Romagnuolo, Joseph
Schellenberg, Gerard D
Sherman, Stuart
Simon, Peter
Singh, Vijay P
Slivka, Adam
Stolz, Donna
Sutton, Robert
Weiss, Frank Ulrich
Wilcox, C Mel
Zarnescu, Narcis Octavian
Wisniewski, Stephen R
O'Connell, Michael R
Kienholz, Michelle L
Roeder, Kathryn
Barmada, M Michael
Yadav, Dhiraj
Devlin, Bernie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510344
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510344
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/ng.2466
