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Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510679

Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

About this item

Full title

Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2010-03, Vol.327 (5973), p.1644-1648

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Extracellular matrices in diverse biological systems are cross-linked by dityrosine covalent bonds catalyzed by the peroxidase/oxidase system. We show that a peroxidase, secreted by the Anopheles gambiae midgut, and dual oxidase form a dityrosine network that decreases gut permeability to immune elicitors. This network protects the microbiota by pr...

Alternative Titles

Full title

Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510679

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510679

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1184008

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