A network of genetic repression and derepression specifies projection fates in the developing neocor...
A network of genetic repression and derepression specifies projection fates in the developing neocortex
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Neurons within each layer in the mammalian cortex have Stereotypic projections. Four genes—Fezf2, Ctip2, Tbr1, and Satb2—regulate these projection identities. These genes also interact with each other, and it is unclear how these interactions shape the final projection identity. Here we show, by generating double mutants of Fezf2, Ctip2, and Satb2,...
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A network of genetic repression and derepression specifies projection fates in the developing neocortex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3511157
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3511157
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1216793109