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A network of genetic repression and derepression specifies projection fates in the developing neocor...

A network of genetic repression and derepression specifies projection fates in the developing neocor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3511157

A network of genetic repression and derepression specifies projection fates in the developing neocortex

About this item

Full title

A network of genetic repression and derepression specifies projection fates in the developing neocortex

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19071-19078

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Neurons within each layer in the mammalian cortex have Stereotypic projections. Four genes—Fezf2, Ctip2, Tbr1, and Satb2—regulate these projection identities. These genes also interact with each other, and it is unclear how these interactions shape the final projection identity. Here we show, by generating double mutants of Fezf2, Ctip2, and Satb2,...

Alternative Titles

Full title

A network of genetic repression and derepression specifies projection fates in the developing neocortex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3511157

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3511157

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1216793109

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