MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
About this item
Full title
Author / Creator
Mallilankaraman, Karthik , Cárdenas, César , Doonan, Patrick J. , Chandramoorthy, Harish C. , Irrinki, Krishna M. , Golenár, Tünde , Csordás, György , Madireddi, Priyanka , Yang, Jun , Müller, Marioly , Miller, Russell , Kolesar, Jill E. , Molgó, Jordi , Kaufman, Brett , Hajnóczky, György , Foskett, J. Kevin and Madesh, Muniswamy
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The mitochondrial calcium uniporter (MCU) mediates calcium uptake by mitochondria and thus regulates cellular bioenergetics, but how MCU activity is modulated is not fully understood. Madesh, Foskett and colleagues report that the integral mitochondrial membrane protein MCUR1 (mitochondrial calcium uniporter regulator 1) binds to the MCU and promot...
Alternative Titles
Full title
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3511605
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3511605
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2622
