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TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3512387

TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

About this item

Full title

TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2012-11, Vol.31 (23), p.4404-4414

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Tumour necrosis factor alpha (TNFα) is a potent cytokine that signals through nuclear factor kappa B (NFκB) to activate a subset of human genes. It is usually assumed that this involves RNA polymerases transcribing responsive genes wherever they might be in the nucleus. Using primary human endothelial cells, variants of chromosome conformation capt...

Alternative Titles

Full title

TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3512387

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3512387

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2012.288

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