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The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis

The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3513968

The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis

About this item

Full title

The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2012-12, Vol.2 (1), p.919-919, Article 919

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Anomalous expansion of a polymorphic tract in Ataxin-1 causes the autosomal dominant spinocerebellar ataxia type 1. In addition to polyglutamine expansion, requirements for development of pathology are phosphorylation of serine 776 in Ataxin-1 and nuclear localization of the protein. The phosphorylation state of serine 776 is also crucial for selec...

Alternative Titles

Full title

The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3513968

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3513968

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep00919

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