Structure and dynamics of the M3 muscarinic acetylcholine receptor
Structure and dynamics of the M3 muscarinic acetylcholine receptor
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The X-ray crystal structure of the M3 muscarinic acetylcholine receptor bound to the bronchodilator drug tiotropium is reported; comparison of this structure with that of the M2 muscarinic acetylcholine receptor reveals key differences that could potentially be exploited to develop subtype-selective drugs.
Muscrarinic receptor structures compare...
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Full title
Structure and dynamics of the M3 muscarinic acetylcholine receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3529910
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3529910
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10867
