Defective Tumor Necrosis Factor Release from Crohn's Disease Macrophages in Response to Toll-like Re...
Defective Tumor Necrosis Factor Release from Crohn's Disease Macrophages in Response to Toll-like Receptor Activation: Relationship to Phenotype and Genome-wide Association Susceptibility Loci
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Oxford, UK: Oxford University Press
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Language
English
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Oxford, UK: Oxford University Press
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BackgroundRecent work provides evidence of a failure of acute inflammation in Crohn's disease (CD), and suggests that the primary defect operates at the level of the macrophage and cytokine release. Here we extend the characterization of the innate immune defect in CD by investigating the macrophage response to Toll-like receptor (TLR) agonists and...
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Full title
Defective Tumor Necrosis Factor Release from Crohn's Disease Macrophages in Response to Toll-like Receptor Activation: Relationship to Phenotype and Genome-wide Association Susceptibility Loci
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3532612
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3532612
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ISSN
1078-0998
E-ISSN
1536-4844
DOI
10.1002/ibd.22952
