The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism
The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Postprandially, the liver experiences an extensive metabolic reprogramming that is required for the switch from glucose production to glucose assimilation. Upon refeeding, the unfolded protein response (UPR) is rapidly, though only transiently, activated. Activation of the UPR results in a cessation of protein translation, increased chaperone expre...
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Full title
The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533268
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533268
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI62819