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The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533268

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

About this item

Full title

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2013-01, Vol.123 (1), p.455-468

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Postprandially, the liver experiences an extensive metabolic reprogramming that is required for the switch from glucose production to glucose assimilation. Upon refeeding, the unfolded protein response (UPR) is rapidly, though only transiently, activated. Activation of the UPR results in a cessation of protein translation, increased chaperone expre...

Alternative Titles

Full title

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533268

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533268

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI62819

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