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TGF-β upregulates miR-181a expression to promote breast cancer metastasis

TGF-β upregulates miR-181a expression to promote breast cancer metastasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533297

TGF-β upregulates miR-181a expression to promote breast cancer metastasis

About this item

Full title

TGF-β upregulates miR-181a expression to promote breast cancer metastasis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2013-01, Vol.123 (1), p.150-163

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Late-stage breast cancer metastasis is driven by dysregulated TGF-β signaling, but the underlying molecular mechanisms have not been fully elucidated. We attempted to recapitulate tumor and metastatic microenvironments via the use of biomechanically compliant or rigid 3D organotypic cultures and combined them with global microRNA (miR) profiling an...

Alternative Titles

Full title

TGF-β upregulates miR-181a expression to promote breast cancer metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533297

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533297

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI64946

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