Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus
Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus
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Author / Creator
Rodig, Scott J , Cheng, Jingwei , Wardzala, Jacek , DoRosario, Andrew , Scanlon, Jessica J , Laga, Alvaro C , Martinez-Fernandez, Alejandro , Barletta, Justine A , Bellizzi, Andrew M , Sadasivam, Subhashini , Holloway, Dustin T , Cooper, Dylan J , Kupper, Thomas S , Wang, Linda C and DeCaprio, James A
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
A human polyomavirus was recently discovered in Merkel cell carcinoma (MCC) specimens. The Merkel cell polyomavirus (MCPyV) genome undergoes clonal integration into the host cell chromosomes of MCC tumors and expresses small T antigen and truncated large T antigen. Previous studies have consistently reported that MCPyV can be detected in approximat...
Alternative Titles
Full title
Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3533549
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI64116
