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Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3535352

Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

About this item

Full title

Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Acta neuropathologica, 2013-01, Vol.125 (1), p.111-120

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

The blood–brain barrier and blood–spinal cord barrier (BSCB) limit the entry of plasma components and erythrocytes into the central nervous system (CNS). Pericytes play a key role in maintaining blood–CNS barriers. The BSCB is damaged in patients with amyotrophic lateral sclerosis (ALS). Moreover, transgenic ALS rodents and pericyte-deficient mice...

Alternative Titles

Full title

Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3535352

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3535352

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-012-1039-8

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