Catalytic Consumption of Nitric Oxide by 12/15-Lipoxygenase: Inhibition of Monocyte Soluble Guanylat...
Catalytic Consumption of Nitric Oxide by 12/15-Lipoxygenase: Inhibition of Monocyte Soluble Guanylate Cyclase Activation
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
12/15-Lipoxygenase (LOX) activity is elevated in vascular diseases associated with impaired nitric oxide (·NO) bioactivity, such as hypertension and atherosclerosis. In this study, primary porcine monocytes expressing 12/15-LOX, rat A10 smooth muscle cells transfected with murine 12/15-LOX, and purified porcine 12/15-LOX all consumed·NO in the pres...
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Full title
Catalytic Consumption of Nitric Oxide by 12/15-Lipoxygenase: Inhibition of Monocyte Soluble Guanylate Cyclase Activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_35458
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_35458
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.141136098