The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation
The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation
About this item
Full title
Author / Creator
Publisher
United States: American Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Thoracic Society
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Scope and Contents
Contents
Increased NADP reduced (NADPH) oxidase 4 (Nox4) and reduced expression of the nuclear hormone receptor peroxisome proliferator-activated receptor γ (PPARγ) contribute to hypoxia-induced pulmonary hypertension (PH). To examine the role of Nox4 activity in pulmonary vascular cell proliferation and PH, the current study used a novel Nox4 inhibitor, GK...
Alternative Titles
Full title
The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3547100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3547100
Other Identifiers
ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2011-0418OC
