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In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface

In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3549482

In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface

About this item

Full title

In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface

Publisher

England: John Wiley & Sons, Inc

Journal title

Cellular microbiology, 2012-12, Vol.14 (12), p.1892-1903

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Summary
Hepatitis C virus (HCV) entry is dependent on host cell molecules tetraspanin CD81, scavenger receptor BI and tight junction proteins claudin‐1 and occludin. We previously reported a role for CD81/claudin‐1 receptor complexes in HCV entry; however, the molecular mechanism(s) driving association between the receptors is unknown. We explor...

Alternative Titles

Full title

In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3549482

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3549482

Other Identifiers

ISSN

1462-5814

E-ISSN

1462-5822

DOI

10.1111/cmi.12008

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