In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface
In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Summary
Hepatitis C virus (HCV) entry is dependent on host cell molecules tetraspanin CD81, scavenger receptor BI and tight junction proteins claudin‐1 and occludin. We previously reported a role for CD81/claudin‐1 receptor complexes in HCV entry; however, the molecular mechanism(s) driving association between the receptors is unknown. We explor...
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Full title
In silico directed mutagenesis identifies the CD81/claudin‐1 hepatitis C virus receptor interface
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3549482
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3549482
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ISSN
1462-5814
E-ISSN
1462-5822
DOI
10.1111/cmi.12008