A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
FOXO3 is a negative regulator of IRF7, a master regulator of the antiviral response.
Taming the antiviral response
Antiviral responses must be tightly regulated if they are to effectively defend against infection yet keep collateral damage to a minimum. Using a systems-biology approach, Vladimir Litvak
et al
. identify the transcription...
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Full title
A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3556990
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3556990
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11428
