DNA interstrand crosslink repair and cancer
DNA interstrand crosslink repair and cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
DNA interstrand crosslinks (ICLs) may arise following exposure to environmental mutagens, and are potently toxic when induced in large numbers by chemotherapeutic drugs. ICL-based chemotherapy is one of the most widely used forms of cancer treatment, particularly in the treatment of leukaemias.
Fanconi anaemia (FA) is a disorder th...
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Full title
DNA interstrand crosslink repair and cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3560328
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3560328
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ISSN
1474-175X,1474-1768
E-ISSN
1474-1768
DOI
10.1038/nrc3088