Role for the obesity-related FTO gene in the cellular sensing of amino acids
Role for the obesity-related FTO gene in the cellular sensing of amino acids
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
SNPs in the first intron of FTO (fat mass and obesity associated) are strongly associated with human obesity. While it is not yet formally established that this effect is mediated through the actions of the FTO protein itself, loss of function mutations in FTO or its murine homologue Fto result in severe growth retardation, and mice globally overex...
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Full title
Role for the obesity-related FTO gene in the cellular sensing of amino acids
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3574930
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3574930
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1222796110
