Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Pharmacokinetic analysis at the organ level provides insight into how drugs distribute throughout the body, but cannot explain how drugs work at the cellular level. Here we demonstrate
in vivo
single-cell pharmacokinetic imaging of PARP-1 inhibitors and model drug behaviour under varying conditions. We visualize intracellular kinetics of the...
Alternative Titles
Full title
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3579506
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3579506
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms2506
