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Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Sc...

Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Sc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3590994

Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Scc1 gate

About this item

Full title

Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Scc1 gate

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2013-03, Vol.32 (5), p.666-676

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Faithful transmission of chromosomes during eukaryotic cell division requires sister chromatids to be paired from their generation in S phase until their separation in M phase. Cohesion is mediated by the cohesin complex, whose Smc1, Smc3 and Scc1 subunits form a tripartite ring that entraps both DNA double strands. Whereas centromeric cohesin is r...

Alternative Titles

Full title

Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Scc1 gate

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3590994

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3590994

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2013.7

How to access this item