Full-length Gαq–phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain
Full-length Gαq–phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The regulatory importance of the C-terminal coiled-coil domain of PLCβ has long been known yet remains poorly understood. The crystal structure and cryo-EM reconstruction of full-length PLCβ3 bound to its activator Gα
q
reveals that the C terminus makes contact with both the catalytic core and Gα
q
to contribute to the complex regulatio...
Alternative Titles
Full title
Full-length Gαq–phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3594540
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3594540
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2497
