Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated...
Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Group I metabotropic glutamate receptors (mGluR) are coupled via Gαq/11 to the activation of phospholipase Cβ, which hydrolyzes membrane phospholipids to form inositol 1,4,5 trisphosphate and diacylglycerol. In addition to functioning as neurotransmitter receptors to modulate synaptic activity, pathological mGluR5 signaling has been implicated in a...
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Full title
Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3598502
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3598502
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ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/1756-6606-6-9
