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Central dogma at the single-molecule level in living cells

Central dogma at the single-molecule level in living cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3600414

Central dogma at the single-molecule level in living cells

About this item

Full title

Central dogma at the single-molecule level in living cells

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2011-07, Vol.475 (7356), p.308-315

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Gene expression originates from individual DNA molecules within living cells. Like many single-molecule processes, gene expression and regulation are stochastic, that is, sporadic in time. This leads to heterogeneity in the messenger-RNA and protein copy numbers in a population of cells with identical genomes. With advanced single-cell fluorescence...

Alternative Titles

Full title

Central dogma at the single-molecule level in living cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3600414

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3600414

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature10315

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