Central dogma at the single-molecule level in living cells
Central dogma at the single-molecule level in living cells
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Gene expression originates from individual DNA molecules within living cells. Like many single-molecule processes, gene expression and regulation are stochastic, that is, sporadic in time. This leads to heterogeneity in the messenger-RNA and protein copy numbers in a population of cells with identical genomes. With advanced single-cell fluorescence...
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Central dogma at the single-molecule level in living cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3600414
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3600414
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10315