The aged niche disrupts muscle stem cell quiescence
The aged niche disrupts muscle stem cell quiescence
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The niche is a conserved regulator of stem cell quiescence and function. During ageing, stem cell function declines. To what extent and by what means age-related changes within the niche contribute to this phenomenon are unknown. Here we demonstrate that the aged muscle stem cell niche, the muscle fibre, expresses Fgf2 under homeostatic conditions,...
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Full title
The aged niche disrupts muscle stem cell quiescence
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3605795
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3605795
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11438
