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Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor...

Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3613249

Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib

About this item

Full title

Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib

Publisher

Australia: Blackwell Publishing Ltd

Journal title

Clinical and experimental pharmacology & physiology, 2012-05, Vol.39 (5), p.454-461

Language

English

Formats

Publication information

Publisher

Australia: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

Summary
Vascular endothelial growth factor inhibitors (VEGFi) are known to cause hypertension and renal injury that severely limits their use as an anticancer therapy. We hypothesized that the angiotensin‐converting enzyme inhibitor captopril not only prevents hypertension, but also decreases renal injury caused by the VEGFi sorafenib.
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Alternative Titles

Full title

Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3613249

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3613249

Other Identifiers

ISSN

0305-1870

E-ISSN

1440-1681

DOI

10.1111/j.1440-1681.2012.05699.x

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