Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Contents
Despite considerable interest in the modulation of tumor-associated Foxp3 + regulatory T cells (T regs ) for therapeutic benefit, little is known about the developmental origins of these cells and the nature of the antigens that they recognize. We identified an endogenous population of antigen-specific T regs (termed MJ23 T regs ) found recurrently...
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Full title
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3622085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3622085
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1233913