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Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells

Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3622085

Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells

About this item

Full title

Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6124), p.1219-1224

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Despite considerable interest in the modulation of tumor-associated Foxp3 + regulatory T cells (T regs ) for therapeutic benefit, little is known about the developmental origins of these cells and the nature of the antigens that they recognize. We identified an endogenous population of antigen-specific T regs (termed MJ23 T regs ) found recurrently...

Alternative Titles

Full title

Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3622085

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3622085

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1233913

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