Inter-α/β subunits coupling mediating pre-inactivation and augmented activation of BKCa(β2)
Inter-α/β subunits coupling mediating pre-inactivation and augmented activation of BKCa(β2)
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Author / Creator
Hou, Panpan , Zeng, Wenping , Gan, Geliang , Lv, Caixia , Guo, Xiying , Zhang, Zheng , Liu, Haowen , Wu, Ying , Yao, Jing , Wei, Aguan D. , Wang, Sheng and Ding, Jiuping
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Large-conductance calcium-activated potassium (BK) channels regulate the electric properties and neurotransmitter release in excitable cells. Its auxiliary β2 subunits not only enhance gating, but also confer inactivation via a short-lived preinactivated state. However, the mechanism of enhancement and preinactivation of BK channels by β2 remains e...
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Full title
Inter-α/β subunits coupling mediating pre-inactivation and augmented activation of BKCa(β2)
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3627188
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3627188
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep01666